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Identifying Suitable Three-Dimensional Bio-Printed Scaffold Architectures to Incubate in a Perfusion Bioreactor: Simulation and Experimental Approaches
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Traditional cell culturing methods are limited in their ability to supply growth medium to cells within scaffolds. To address this, we developed a custom perfusion bioreactor that allows for dynamic medium supply to ...
Designing an Interchangeable Multi-Material Nozzle System for the Three-Dimensional Bioprinting Process
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Three-dimensional bioprinting is a rapidly growing field attempting to recreate functional tissues for medical and pharmaceutical purposes. Development of functional tissue requires deposition of multiple biomaterials ...
Fiber-Filled Hybrid Hydrogel for Bio-Manufacturing
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Extrusion-based three-dimensional (3D) bio-printing deposits cell-laden bio-ink with high spatial resolution and may offer living tissue regeneration. Due to the biocompatibility, very low cytotoxicity, and high-water ...
A Roadmap to Fabricate Geometrically Accurate ThreeDimensional Scaffolds COPrinted by Natural and Synthetic Polymers
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Threedimensional bioprinting is a promising field in regenerating patientspecific tissues and organs due to its inherent capability of releasing biocompatible materials encapsulating living cells in a predefined location. ...
Physical Modification of Hybrid Hydrogels to Fabricate FullScale Construct Using ThreeDimensional BioPrinting Process
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Bioprinting for regenerative medicine has been gaining a lot of popularity in today's world. Despite being one of the rigorously studied fields, there are still several challenges yet to be solved. Geometric fidelity and ...
Design and Fabrication of In-House Nozzle System to Extrude Multi-Hydrogels for 3D Bioprinting Process
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The field of 3D bioprinting is rapidly expanding as researchers strive to create functional tissues for medical and pharmaceutical purposes. The ability to print multiple materials, each containing various living cells, ...
Integrating Decision Trees and Clustering for Efficient Optimization of Bioink Rheology and 3D Bioprinted Construct Microenvironments
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Among various 3D bioprinting methods, extrusion-based bioprinting stands out for its ability to maintain high cell viability and create intricate scaffold structures. However, working with synthetic polymers or natural ...