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RISOn the Functional Role of Valve Interstitial Cell Stress Fibers: A Continuum Modeling Approach
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The function of the heart valve interstitial cells (VICs) is intimately connected to heart valve tissue remodeling and repair, as well as the onset and progression of valvular pathological processes. There is yet only very ...
Perspectives on Sharing Models and Related Resources in Computational Biomechanics Research
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The role of computational modeling for biomechanics research and related clinical care will be increasingly prominent. The biomechanics community has been developing computational models routinely for exploration of the ...
Combined Experimental Approach and Finite Element Modeling of Small Molecule Transport Through Joint Synovium to Measure Effective Diffusivity
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Trans-synovial solute transport plays a critical role in the clearance of intra-articularly (IA) delivered drugs. In this study, we present a computational finite element model (FEM) of solute transport through the synovium ...