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    Models of Shear-Induced Platelet Activation and Numerical Implementation With Computational Fluid Dynamics Approaches 

    Source: Journal of Biomechanical Engineering:;2021:;volume( 144 ):;issue: 004:;page 40801-1
    Author(s): Han, Dong; Zhang, Jiafeng; Griffith, Bartley P.; Wu, Zhongjun J.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Shear-induced platelet activation is one of the critical outcomes when blood is exposed to elevated shear stress. Excessively activated platelets in the circulation can lead to thrombus formation and platelet consumption, ...
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    Model-Based Design and Optimization of Blood Oxygenators 

    Source: Journal of Medical Devices:;2020:;volume( 014 ):;issue: 004:;page 041001-1
    Author(s): He, Ge; Zhang, Tao; Zhang, Jiafeng; Griffith, Bartley P.; Wu, Zhongjun J.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Blood oxygenators, also known as artificial lungs, are widely used in cardiopulmonary bypass surgery to maintain physiologic oxygen (O2) and carbon dioxide (CO2) levels in blood, and also serve as respiratory assist devices ...
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    Computational Study of the Blood Flow in Three Types of 3D Hollow Fiber Membrane Bundles 

    Source: Journal of Biomechanical Engineering:;2013:;volume( 135 ):;issue: 012:;page 121009
    Author(s): Zhang, Jiafeng; Chen, Xiaobing; Ding, Jun; Fraser, Katharine H.; Ertan Taskin, M.; Griffith, Bartley P.; Wu, Zhongjun J.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: The goal of this study is to develop a computational fluid dynamics (CFD) modeling approach to better estimate the blood flow dynamics in the bundles of the hollow fiber membrane based medical devices (i.e., blood oxygenators, ...
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