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Simulated Effects of Acute Left Ventricular Myocardial Infarction on Mitral Regurgitation in an Ovine Model
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Ischemic mitral regurgitation (IMR) occurs from incomplete coaptation of the mitral valve (MV) after myocardial infarction (MI), typically worsened by continued remodeling of the left ventricular (LV). The importance of ...
A Computational Pipeline for Patient-Specific Prediction of the Postoperative Mitral Valve Functional State
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: While mitral valve (MV) repair remains the preferred clinical option for mitral regurgitation (MR) treatment, long-term outcomes remain suboptimal and difficult to predict. Furthermore, pre-operative optimization is ...
On the Simulation of Mitral Valve Function in Health, Disease, and Treatment
Publisher: American Society of Mechanical Engineers (ASME)
Abstract: The mitral valve (MV) is the left atrioventricular heart valve that regulates blood flow between the left atrium and left ventricle (LV) during the cardiac cycle. Contrary to the aortic valve (AV), the MV is an intimately ...
Computational Investigation of Transmural Differences in Left Ventricular Contractility
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Myocardial contractility of the left ventricle (LV) plays an essential role in maintaining normal pump function. A recent ex vivo experimental study showed that cardiomyocyte force generation varies across the three ...
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