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    Volume Loss and Recovery in Bovine Knee Meniscus Loaded in Circumferential Tension 

    Source: Journal of Biomechanical Engineering:;2023:;volume( 145 ):;issue: 007:;page 71009-1
    Author(s): Peloquin, John M.; Santare, Michael H.; Elliott, Dawn M.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Load-induced volume change is an important aspect of knee meniscus function because volume loss creates fluid pressure, which minimizes friction and helps support compressive loads. The knee meniscus is unusual amongst ...
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    Advances in Quantification of Meniscus Tensile Mechanics Including Nonlinearity, Yield, and Failure 

    Source: Journal of Biomechanical Engineering:;2016:;volume( 138 ):;issue: 002:;page 21002
    Author(s): Peloquin, John M.; Santare, Michael H.; Elliott, Dawn M.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: The meniscus provides crucial knee function and damage to it leads to osteoarthritis of the articular cartilage. Accurate measurement of its mechanical properties is therefore important, but there is uncertainty about how ...
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    A Reactive Inelasticity Theoretical Framework for Modeling Viscoelasticity, Plastic Deformation, and Damage in Fibrous Soft Tissue 

    Source: Journal of Biomechanical Engineering:;2019:;volume( 141 ):;issue: 002:;page 21005
    Author(s): Safa, Babak N.; Santare, Michael H.; Elliott, Dawn M.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Fibrous soft tissues are biopolymeric materials that are made of extracellular proteins, such as different types of collagen and proteoglycans, and have a high water content. These tissues have nonlinear, anisotropic, and ...
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    Acute Repair of Meniscus Root Tear Partially Restores Joint Displacements as Measured With Magnetic Resonance Images and Loading in a Cadaveric Porcine Knee 

    Source: Journal of Biomechanical Engineering:;2023:;volume( 145 ):;issue: 008:;page 81002-1
    Author(s): Meadows, Kyle D.; Peloquin, John M.; Markhali, Milad I.; Zgonis, Miltiadis H.; Schaer, Thomas P.; Mauck, Robert L.; Elliott, Dawn M.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: The meniscus serves important load-bearing functions and protects the underlying articular cartilage. Unfortunately, meniscus tears are common and impair the ability of the meniscus to distribute loads, increasing the risk ...
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    Biaxial Tension of Fibrous Tissue: Using Finite Element Methods to Address Experimental Challenges Arising From Boundary Conditions and Anisotropy 

    Source: Journal of Biomechanical Engineering:;2013:;volume( 135 ):;issue: 002:;page 21004
    Author(s): Jacobs, Nathan T.; Cortes, Daniel H.; Vresilovic, Edward J.; Elliott, Dawn M.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Planar biaxial tension remains a critical loading modality for fibrous soft tissue and is widely used to characterize tissue mechanical response, evaluate treatments, develop constitutive formulas, and obtain material ...
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    Evaluation of an In Situ Gelable and Injectable Hydrogel Treatment to Preserve Human Disc Mechanical Function Undergoing Physiologic Cyclic Loading Followed by Hydrated Recovery 

    Source: Journal of Biomechanical Engineering:;2015:;volume( 137 ):;issue: 008:;page 81008
    Author(s): Showalter, Brent L.; Elliott, Dawn M.; Chen, Weiliam; Malhotra, Neil R.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Despite the prevalence of disc degeneration and its contributions to low back problems, many current treatments are palliative only and ultimately fail. To address this, nucleus pulposus replacements are under development. ...
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    Evaluating Plastic Deformation and Damage as Potential Mechanisms for Tendon Inelasticity Using a Reactive Modeling Framework 

    Source: Journal of Biomechanical Engineering:;2019:;volume( 141 ):;issue: 010:;page 101008
    Author(s): Safa, Babak N.; Lee, Andrea H.; Santare, Michael H.; Elliott, Dawn M.
    Publisher: American Society of Mechanical Engineers (ASME)
    Abstract: Inelastic behaviors, such as softening, a progressive decrease in modulus before failure, occur in tendon and are important aspects in degeneration and tendinopathy. These inelastic behaviors are generally attributed to ...
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    Overload in a Rat In Vivo Model of Synergist Ablation Induces Tendon Multiscale Structural and Functional Degeneration 

    Source: Journal of Biomechanical Engineering:;2023:;volume( 145 ):;issue: 008:;page 81003-1
    Author(s): Bloom, Ellen T.; Lin, Lily M.; Locke, Ryan C.; Giordani, Alyssa; Krassan, Erin; Peloquin, John M.; Silbernagel, Karin Grävare; Parreno, Justin; Santare, Michael H.; Killian, Megan L.; Elliott, Dawn M.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Tendon degeneration is typically described as an overuse injury with little distinction made between magnitude of load (overload) and number of cycles (overuse). Further, in vivo, animal models of tendon degeneration are ...
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    Internal Three Dimensional Strains in Human Intervertebral Discs Under Axial Compression Quantified Noninvasively by Magnetic Resonance Imaging and Image Registration 

    Source: Journal of Biomechanical Engineering:;2014:;volume( 136 ):;issue: 011:;page 111008
    Author(s): Yoder, Jonathon H.; Peloquin, John M.; Song, Gang; Tustison, Nick J.; Moon, Sung M.; Wright, Alexander C.; Vresilovic, Edward J.; Gee, James C.; Elliott, Dawn M.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Study objectives were to develop, validate, and apply a method to measure threedimensional (3D) internal strains in intact human discs under axial compression. A custombuilt loading device applied compression and permitted ...
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    Human Disc Nucleotomy Alters Annulus Fibrosus Mechanics at Both Reference and Compressed Loads 

    Source: Journal of Biomechanical Engineering:;2019:;volume( 141 ):;issue: 011:;page 111001
    Author(s): Claeson, Amy A.; Vresilovic, Edward J.; Showalter, Brent L.; Wright, Alexander C.; Gee, James C.; Malhotra, Neil R.; Elliott, Dawn M.
    Publisher: American Society of Mechanical Engineers (ASME)
    Abstract: Nucleotomy is a common surgical procedure and is also performed in ex vivo mechanical testing to model decreased nucleus pulposus (NP) pressurization that occurs with degeneration. Here, we implement novel and noninvasive ...
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