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Mathematical Model for Tissue-Level Hypoxic Response in Microfluidic Environment
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Availability of essential species like oxygen is critical in shaping the dynamics of tumor growth. When the intracellular oxygen level falls below normal, it initiates major cascades in cellular dynamics leading to tumor ...
Numerical Modeling of Flow Through Phloem Considering Active Loading
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Transport through phloem is of significant interest in engineering applications, including selfpowered microfluidic pumps. In this paper we present a phloem model, combining protein level mechanics with cellular level fluid ...
Time-Periodic Electro-Osmotic Flow With Nonuniform Surface Charges
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Mixing in a microfluidic device is a major challenge due to creeping flow, which is a significant roadblock for development of lab-on-a-chip device. In this study, an analytical model is presented to study the fluid flow ...