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Influence of Radial Variations in Biochemical Concentrations in Collagen Type and Water on Mechanical Stability of Annulus Fibrosus' Collagen–Hyaluronan Interfaces at Nanoscale: A Molecular Dynamics Investigation
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Multidirectional load transmission ability by annulus fibrosus (AF) requires substantial mechanical stability. Additionally, AF exhibits a unique biochemical concentration gradient with outer AF (OA) dominated by type I ...
Ab Initio Investigation of Strain Dependent Atomistic Interactions at Two Tropocollagen Hydroxyapatite Interfaces
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Tropocollagen (TC) and hydroxyapatite (HAP) interfaces are one of the main load bearing entities in bone family of materials. Atomistic interactions in such interfaces occur in a variety of chemical environments under a ...
Impact of Variations in Water Concentration on the Nanomechanical Behavior of Type I Collagen Microfibrils in Annulus Fibrosus
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Radial variation in water concentration from outer to inner lamellae is one of the characteristic features of annulus fibrosus (AF). In addition, water concentration changes are also associated with intervertebral disc ...