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RISIn Vivo Serial MRI-Based Models and Statistical Methods to Quantify Sensitivity and Specificity of Mechanical Predictors for Carotid Plaque Rupture: Location and Beyond
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: It has been hypothesized that mechanical risk factors may be used to predict future atherosclerotic plaque rupture. Truly predictive methods for plaque rupture and methods to identify the best ...
Steady Flow and Wall Compression in Stenotic Arteries: A Three-Dimensional Thick-Wall Model With Fluid–Wall Interactions
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Severe stenosis may cause critical flow and wall mechanical conditions related to artery fatigue, artery compression, and plaque rupture, which leads directly to heart attack and stroke. The ...
Effect of a Lipid Pool on Stress/Strain Distributions in Stenotic Arteries: 3-D Fluid-Structure Interactions (FSI) Models
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Nonlinear 3-D models with fluid-structure interactions (FSI) based on in vitro experiments are introduced and solved by ADINA to perform flow and stress/strain analysis for stenotic arteries with ...
Patient-Specific MRI-Based 3D FSI RV/LV/Patch Models for Pulmonary Valve Replacement Surgery and Patch Optimization
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: A patient-specific right/left ventricle and patch (RV/LV/patch) combination model with fluid-structure interactions (FSIs) was introduced to evaluate and optimize human pulmonary valve replacement/insertion ...
Quantifying Effect of Intraplaque Hemorrhage on Critical Plaque Wall Stress in Human Atherosclerotic Plaques Using Three-Dimensional Fluid-Structure Interaction Models
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Recent magnetic resonance studies have indicated that intraplaque hemorrhage (IPH) may accelerate plaque progression and play an important role in plaque destabilization. However, the impact of ...
Using In Vivo Cine and 3D Multi-Contrast MRI to Determine Human Atherosclerotic Carotid Artery Material Properties and Circumferential Shrinkage Rate and Their Impact on Stress/Strain Predictions
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: In vivo magnetic resonance image (MRI)-based computational models have been introduced to calculate atherosclerotic plaque stress and strain conditions for possible rupture predictions. However, ...
Quantifying Effects of Plaque Structure and Material Properties on Stress Distributions in Human Atherosclerotic Plaques Using 3D FSI Models
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Background: Atherosclerotic plaques may rupture without warning and cause acute cardiovascular syndromes such as heart attack and stroke. Methods to assess plaque vulnerability noninvasively and ...
3D Critical Plaque Wall Stress Is a Better Predictor of Carotid Plaque Rupture Sites Than Flow Shear Stress: An In Vivo MRI-Based 3D FSI Study
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Atherosclerotic plaque rupture leading to stroke is the major cause of long-term disability as well as the third most common cause of mortality. Image-based computational models have been ...
3D MRI-Based Anisotropic FSI Models With Cyclic Bending for Human Coronary Atherosclerotic Plaque Mechanical Analysis
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Heart attack and stroke are often caused by atherosclerotic plaque rupture, which happens without warning most of the time. Magnetic resonance imaging (MRI)-based atherosclerotic plaque models ...