Abstract: Biomolecular simulations are computationally expensive. Simulating time histories larger than seconds remain elusive even with the help of supercomputers. Biological phenomena are multiscale in nature. The dynamics range ...

Abstract: This paper presents a high-speed approach to simulating the long-term mechanobiological development of stem cells during the adipogenesis process. A novel three-dimensional model of human bone marrow-derived mesenchymal ...

Abstract: Cell mechanics has been shown to regulate stem cell differentiation. We have previously reported that altered cell stiffness of mesenchymal stem cells can delay or facilitate biochemically directed differentiation. One of ...