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RISEffect of Wall Compliance and Permeability on Blood-Flow Rate in Counter-Current Microvessels Formed From Anastomosis During Tumor-Induced Angiogenesis
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Tumor blood-flow is inhomogeneous because of heterogeneity in tumor vasculature, vessel-wall leakiness, and compliance. Experimental studies have shown that normalization of tumor vasculature by ...
A Model for the Modulation of Microvessel Permeability by Junction Strands
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: To investigate the effect of junction strands on microvessel permeability, we extend the previous analytical model developed by Fu et al. (1994, J. Biomech. Eng., 116 , pp. 502–513), for the ...
An Electrodiffusion Model for the Blood-Brain Barrier Permeability to Charged Molecules
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The endothelial surface glycocalyx layer (SGL) and the basement membrane (BM) are two important components of the blood-brain barrier (BBB). They provide large resistance to solute transport ...
An Electrodiffusion-Filtration Model for Effects of Endothelial Surface Glycocalyx on Microvessel Permeability to Macromolecules
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Endothelial surface glycocalyx plays an important role in the regulation of microvessel permeability by possibly changing its charge and configuration. To investigate the mechanisms by which surface ...
Structural Mechanisms in the Abolishment of VEGF-induced Microvascular Hyperpermeability by cAMP
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: To investigate the structural mechanisms by which elevation of the intraendothelial cAMP levels abolishes or attenuates the transient increase in microvascular permeability by vascular endothelial ...
Determination of Microvessel Permeability and Tissue Diffusion Coefficient of Solutes by Laser Scanning Confocal Microscopy
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Interstitium contains a matrix of fibrous molecules that creates considerable resistance to water and solutes in series with the microvessel wall. On the basis of our preliminary studies (, ...