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    Primary Mouse Aortic Smooth Muscle Cells Exhibit Region- and Sex-Dependent Biological Responses In Vitro 

    Source: Journal of Biomechanical Engineering:;2024:;volume( 146 ):;issue: 006:;page 60904-1
    Author(s): Karbasion, Niyousha; Xu, Yujun; Snider, J. Caleb; Bersi, Matthew R.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Despite advancements in elucidating biological mechanisms of cardiovascular remodeling, cardiovascular disease (CVD) remains the leading cause of death worldwide. When stratified by sex, clear differences in CVD prevalence ...
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    Novel Methodology for Characterizing Regional Variations in the Material Properties of Murine Aortas 

    Source: Journal of Biomechanical Engineering:;2016:;volume( 138 ):;issue: 007:;page 71005
    Author(s): Bersi, Matthew R.; Bellini, Chiara; Di Achille, Paolo; Humphrey, Jay D.; Genovese, Katia; Avril, Stأ©phane
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Many vascular disorders, including aortic aneurysms and dissections, are characterized by localized changes in wall composition and structure. Notwithstanding the importance of histopathologic changes that occur at the ...
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    Constitutive Modeling of Mouse Arteries Suggests Changes in Directional Coupling and Extracellular Matrix Remodeling That Depend on Artery Type, Age, Sex, and Elastin Amounts 

    Source: Journal of Biomechanical Engineering:;2024:;volume( 146 ):;issue: 006:;page 60901-1
    Author(s): Kailash, Keshav A.; Hawes, Jie Z.; Cocciolone, Austin J.; Bersi, Matthew R.; Mecham, Robert P.; Wagenseil, Jessica E.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Arterial stiffening occurs during natural aging, is associated with an increased risk of adverse cardiovascular events, and can follow different timelines in males and females. One mechanism of arterial stiffening includes ...
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