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RISCharacterizations and Correlations of Wall Shear Stress in Aneurysmal Flow
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Wall shear stress (WSS) is one of the most studied hemodynamic parameters, used in correlating blood flow to various diseases. The pulsatile nature of blood flow, along with the complex geometries of diseased arteries, ...
Mechanical Platelet Activation Potential in Abdominal Aortic Aneurysms
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Intraluminal thrombus (ILT) in abdominal aortic aneurysms (AAA) has potential implications to aneurysm growth and rupture risk; yet, the mechanisms underlying its development remain poorly understood. Some researchers have ...
Multiscale Kinematic Growth Coupled With Mechanosensitive Systems Biology in Open-Source Software
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Multiscale coupling between cell-scale biology and tissue-scale mechanics is a promising approach for modeling disease growth. In such models, tissue-level growth and remodeling (G&R) are driven by cell-level signaling ...
The Story of Wall Shear Stress in Coronary Artery Atherosclerosis: Biochemical Transport and Mechanotransduction
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Coronary artery atherosclerosis is a local, multifactorial, complex disease, and the leading cause of death in the US. Complex interactions between biochemical transport and biomechanical forces influence disease growth. ...
Variability of Computational Fluid Dynamics Solutions for Pressure and Flow in a Giant Aneurysm: The ASME 2012 Summer Bioengineering Conference CFD Challenge
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Stimulated by a recent controversy regarding pressure drops predicted in a giant aneurysm with a proximal stenosis, the present study sought to assess variability in the prediction of pressures and flow by a wide variety ...