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Axons Pull on the Brain, But Tension Does Not Drive Cortical Folding
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: During human brain development, the cerebral cortex undergoes substantial folding, leading to its characteristic highly convoluted form. Folding is necessary to accommodate the expansion of the ...
A New Method for Measuring Deformation of Folding Surfaces During Morphogenesis
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: During morphogenesis, epithelia (cell sheets) undergo complex deformations as they stretch, bend, and twist to form the embryo. Often these changes in shape create multivalued surfaces that can ...
A New Method to Measure Cortical Growth in the Developing Brain
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Folding of the cerebral cortex is a critical phase of brain development in higher mammals but the biomechanics of folding remain incompletely understood. During folding, the growth of the ...