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Multiscale Mechanical Simulations of Cell Compacted Collagen Gels
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Engineered tissues are commonly stretched or compressed (i.e., conditioned) during culture to stimulate extracellular matrix (ECM) production and to improve the mechanical properties of the growing construct. The relationships ...
Fiber Network Models Predict Enhanced Cell Mechanosensing on Fibrous Gels
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The propagation of mechanical signals through nonlinear fibrous tissues is much more extensive than through continuous synthetic hydrogels. Results from recent studies indicate that increased mechanical propagation arises ...
A Thermal and Biological Analysis of Bone Drilling
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: With the introduction of high-speed cutting tools, clinicians have recognized the potential for thermal damage to the material being cut. Here, we developed a mathematical model of heat transfer caused by drilling bones ...
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