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contributor authorConstante-Amores, C. R.
contributor authorKahouadji, L.
contributor authorWilliams, J. G.
contributor authorTurney, B. W.
contributor authorShin, S.
contributor authorChergui, J.
contributor authorJuric, D.
contributor authorMoulton, D. E.
contributor authorWaters, S. L.
date accessioned2023-11-29T18:44:18Z
date available2023-11-29T18:44:18Z
date copyright2/1/2023 12:00:00 AM
date issued2/1/2023 12:00:00 AM
date issued2023-02-01
identifier issn0148-0731
identifier otherbio_145_05_051007.pdf
identifier urihttp://yetl.yabesh.ir/yetl1/handle/yetl/4294356
description abstractUreteroscopy is a commonly performed medical procedure to treat stones in the kidney and ureter using a ureteroscope. Throughout the procedure, saline is irrigated through the scope to aid visibility and wash-out debris from stone fragmentation. The key challenge that this research addresses is to build a fundamental understanding of the interaction between the kidney stones/stone fragments and the flow dynamics in the renal pelvis flow. We examine the time-dependent flow dynamics inside an idealized renal pelvis in the context of a surgical procedure for kidney stone removal. Here, we examine the time-dependent evolution of these vortical flow structures in three dimensions, and incorporate the presence of rigid kidney stones. We perform direct numerical simulations, solving the transient Navier–Stokes equations in a spherical domain. Our numerical predictions for the flow dynamics in the absence of stones are validated with available experimental and numerical data, and the governing parameters and flow regimes are chosen carefully in order to satisfy several clinical constraints. The results shed light on the crucial role of flow circulation in the renal cavity and its effect on the trajectories of rigid stones. We demonstrate that stones can either be washed out of the cavity along with the fluid, or be trapped in the cavity via their interaction with vortical flow structures. Additionally, we study the effect of multiple stones in the flow field within the cavity in terms of the kinetic energy, entrapped fluid volume, and the clearance rate of a passive tracer modeled via an advection–diffusion equation. We demonstrate that the flow in the presence of stones features a higher vorticity production within the cavity compared with the stone-free cases.
publisherThe American Society of Mechanical Engineers (ASME)
titleRole of Kidney Stones in Renal Pelvis Flow
typeJournal Paper
journal volume145
journal issue5
journal titleJournal of Biomechanical Engineering
identifier doi10.1115/1.4056461
journal fristpage51007-1
journal lastpage51007-12
page12
treeJournal of Biomechanical Engineering:;2023:;volume( 145 ):;issue: 005
contenttypeFulltext


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