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contributor authorKwon, So Yoon
contributor authorYoon, Ki-Cheol
contributor authorKim, Kwang Gi
date accessioned2022-05-08T09:41:26Z
date available2022-05-08T09:41:26Z
date copyright10/28/2021 12:00:00 AM
date issued2021
identifier issn2572-7958
identifier otherjesmdt_005_01_011002.pdf
identifier urihttp://yetl.yabesh.ir/yetl1/handle/yetl/4285461
description abstractMost brain surgeries aim to completely resection a tumor. However, the arrangement of blood vessels around brain tumors is often complex. Moreover, the tumors and blood vessels have similar colors, making it difficult to identify the boundaries between them with the naked eye. Fluorescent staining is a method used to distinguish the borders between brain tumors and blood vessels. The fluorescent contrast agents commonly used to observe tumors are 5-aminolevulinic acid and fluorescein sodium, which have different surgical sensitivities, depending on the type of tumor. In this article, a dual band bandpass filter with dual-wavelength emission for 5-aminolevulinic acid and fluorescein sodium is designed, and the dual-band bandpass filter capable of inducing simultaneous fluorescence emission of fluorescein sodium and 5-aminolevulinic acid was investigated experimentally to improve accuracy, speed, and energy efficiency in clinical settings. The possibility of dual fluorescence emission with a single irradiation is proposed. The efficiency of transmission and reflection (optical density) is 98% and 0.01%, respectively, and the bandwidth is 50% in the proposed filter. The proposed fluorescent dual-band filter has the advantage of saving energy, reducing auxiliary manpower and unit costs, and reducing operating room space requirements by producing two fluorescence diagnostic effects using a single equipment.
publisherThe American Society of Mechanical Engineers (ASME)
titleDual Fluorescence Emission by Irradiation of Single Optical Source for Fluorescein Sodium and 5-ALA Applications
typeJournal Paper
journal volume5
journal issue1
journal titleJournal of Engineering and Science in Medical Diagnostics and Therapy
identifier doi10.1115/1.4052665
journal fristpage11002-1
journal lastpage11002-5
page5
treeJournal of Engineering and Science in Medical Diagnostics and Therapy:;2021:;volume( 005 ):;issue: 001
contenttypeFulltext


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