Journal of Biomechanical Engineering: Recent submissions
Now showing items 441-460 of 5302
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Strain-Dependent Diffusivity of Small and Large Molecules in Meniscus
(The American Society of Mechanical Engineers (ASME), 2022)Due to lack of full vascularization, the meniscus relies on diffusion through the extracellular matrix to deliver small (e.g., nutrients) and large (e.g., proteins) to resident cells. Under normal physiological conditions, ... -
Emulating the Effective Ankle Stiffness of Commercial Prosthetic Feet Using a Robotic Prosthetic Foot Emulator
(The American Society of Mechanical Engineers (ASME), 2022)Prosthetic foot selection for individuals with lower limb amputation relies primarily on clinician judgment. The prosthesis user rarely has an opportunity to provide experiential input into the decision by trying different ... -
Model-Based Acetabular Cup Orientation Optimization Based on Minimizing the Risk of Edge-Loading and Implant Impingement Following Total Hip Arthroplasty
(The American Society of Mechanical Engineers (ASME), 2022)In this paper, a computationally efficient model-based method for determining patient-specific optimal acetabular cup alignment for total hip arthroplasty (THA) is presented. The proposed algorithm minimizes the risk of ... -
Effect of Simulated Mass-Tunable Auxetic Midsole on Vertical Ground Reaction Force
(The American Society of Mechanical Engineers (ASME), 2022)When runners impact the ground, they experience a sudden peak ground reaction force (GRF), which may be up to 4× greater than their bodyweight. Increased GRF impact peak magnitude has been associated with lower limb injuries ... -
Enhancing the Vortex Whistle for Measures of Respiratory Capacity Via Computational Fluid Dynamics and Computational Aero-Acoustic Analysis
(The American Society of Mechanical Engineers (ASME), 2022)A vortex whistle produces a fundamental frequency proportional to the inlet flowrate. Recent investigations using vortex whistles have focused on the use of this relationship to quantify aspects of respiratory function. ... -
Effects of Gas Embolism on Pulsatile Flow Characteristics Within a Human Carotid Artery
(The American Society of Mechanical Engineers (ASME), 2022)Atherosclerosis in carotid arteries depends mostly on hemodynamic parameters, and any disturbances in pulsatile flows may alter the hemodynamic parameters extensively. Gas emboli are one such source that can hinder and ... -
Guiding the Prostatic Artery Embolization Procedure With Computational Fluid Dynamics
(The American Society of Mechanical Engineers (ASME), 2022)Benign prostatic hyperplasia (BPH) is a common disease associated with lower urinary tract symptoms and is the most frequent benign tumor in men. To reduce BPH therapy complications, prostatic artery embolization (PAE) was ... -
Constant Pressure Convection-Enhanced Delivery Increases Volume Dispersed With Catheter Movement in Agarose
(The American Society of Mechanical Engineers (ASME), 2022)Convection-enhanced delivery (CED) has been extensively studied for drug delivery to the brain due to its inherent ability to bypass the blood-brain barrier. Unfortunately, CED has also been shown to inadequately distribute ... -
Design and Preliminary Evaluation of a Wearable Passive Cam-Based Shoulder Exoskeleton
(The American Society of Mechanical Engineers (ASME), 2022)Mechanically passive exoskeletons may be a practical and affordable solution to meet a growing clinical need for continuous, home-based movement assistance. We designed, fabricated, and preliminarily evaluated the performance ... -
Three-Dimensional Biomechanical Modeling for Sitting Contact Stress Analysis
(The American Society of Mechanical Engineers (ASME), 2022)This paper proposes a three-dimensional biomechanical model of the upper body and analyzes the interaction between the upper body and aircraft seat backrest for different sitting postures and backrest recline angles. The ... -
Characterization of Puncture Forces of the Human Trachea and Cricothyroid Membrane
(The American Society of Mechanical Engineers (ASME), 2022)Accurate human tissue biomechanical data represents a critical knowledge gap that will help facilitate the advancement of new medical devices, patient-specific predictive models, and training simulators. Tissues related ... -
A Review of Head Injury Metrics Used in Automotive Safety and Sports Protective Equipment
(The American Society of Mechanical Engineers (ASME), 2022)Despite advances in the understanding of human tolerances to brain injury, injury metrics used in automotive safety and protective equipment standards have changed little since they were first implemented nearly a half-century ... -
Comparison of Balloon-Expandable Valve and Self-Expandable Valve in Transcatheter Aortic Valve Replacement: A Patient-Specific Numerical Study
(The American Society of Mechanical Engineers (ASME), 2022)Transcatheter aortic valve replacement (TAVR) is a minimally invasive strategy for the treatment of aortic stenosis. The complex postoperative complications of TAVR were related to the type of implanted prosthetic valve, ... -
A Computational Framework for Atrioventricular Valve Modeling Using Open-Source Software
(The American Society of Mechanical Engineers (ASME), 2022)Atrioventricular valve regurgitation is a significant cause of morbidity and mortality in patients with acquired and congenital cardiac valve disease. Image-derived computational modeling of atrioventricular valves has ... -
Bone Remodeling Around Solid and Porous Interbody Cages in the Lumbar Spine
(The American Society of Mechanical Engineers (ASME), 2022)Spinal fusion is an effective surgical treatment for intervertebral disk degeneration. However, the consequences of implantation with interbody cages on load transfer and bone remodeling in the vertebral bodies have scarcely ... -
Lethal Electric Field Thresholds for Cerebral Cells With Irreversible Electroporation and H-FIRE Protocols: An In Vitro Three-Dimensional Cell Model Study
(The American Society of Mechanical Engineers (ASME), 2022)The lethal electric field (LEF) thresholds for three typical cerebral cells, including a malignant glioblastoma (GBM) cell line and two cell lines from the healthy blood-brain barrier (BBB), treated by irreversible ... -
Development of a Strain-Based Model to Predict Eviscerated Thoracic Response From Dynamic Individual Rib Tests
(The American Society of Mechanical Engineers (ASME), 2022)The objective of this study was to develop an analytical model using strain–force relationships from individual rib and eviscerated thorax impacts to predict bony thoracic response. Experimental eviscerated thorax forces ... -
The Effects of Implantation Orientation of a Bileaflet Mechanical Heart Valve in an Anatomic Left Ventricle-Aorta Configuration
(The American Society of Mechanical Engineers (ASME), 2022)We have performed three-dimensional high-resolution numerical simulations of a bi-leaflet mechanical heart valve implanted at different orientations in an anatomic left ventricle-aorta obtained from magnetic resonance ... -
Development of a Finite Element Model of the Pediatric Thoracic and Lumbar Spine, Ribcage, and Pelvis With Orthotropic Region-Specific Vertebral Growth
(The American Society of Mechanical Engineers (ASME), 2022)Finite element (FE) modeling of the spine has increasingly been applied in orthopedic precision-medicine approaches. Previously published FE models of the pediatric spine growth have made simplifications in the geometry ... -
An Electromyography-Based Constitutive Law for Force Generation in Skeletal Muscle—Part II: Model Validation on the Ankle Joint Complex
(The American Society of Mechanical Engineers (ASME), 2022)Part II of this study evaluates the predictive ability of the skeletal muscle force model derived in Part I within the ankle joint complex. The model is founded in dimensional analysis and uses electromyography and the ...