Now showing items 41-60 of 5302
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Magnetic Resonance Imaging-Based Cohesive Extended Finite Element Modeling of Atypical Femoral Fracture
(The American Society of Mechanical Engineers (ASME), 2026)Abstract. Atypical femoral fracture (AFF) is a rare fracture associated with prolonged bisphosphonate (BP) treatment that occurs in the subtrochanter and midshaft of the femur. The association of AFF with BP treatment ... -
Ergonomically Designed Crutches Decrease Ground Reaction Forces, Joint Moments, and Underarm Pressure Compared to Standard Crutches During Walking
(The American Society of Mechanical Engineers (ASME), 2026)Abstract. Studies show that crutch walking is slower than unassisted walking, requires more energy, and may introduce risk factors for injuries in the arms and/or the healthy leg. This study compared the differences between ... -
Optimization of Narrow Cavity Flow Field Via a Passive Self-Exciting Slot Jet for Root Canal Irrigation
(The American Society of Mechanical Engineers (ASME), 2026)Abstract. Root canal treatment is crucial for preventing oral diseases, and its success hinges on the effective removal of biofilm and debris from the canal wall by the irrigant. However, the intricate and narrow anatomy ... -
Numerical Simulations of In-Plane and Transmural Tear Propagations in Aortic Dissection: Possible Mechanisms Behind Dissection Progression
(The American Society of Mechanical Engineers (ASME), 2026)Abstract. The early development of aortic dissections (AD) is manifested by tear propagation. The direction and extent of tear propagation are important for surgical strategy selection and outcomes, yet the mechanism ... -
Population Variations in Helmet Fit Affect Calculated Head Injury Risk in Blunt Impact
(The American Society of Mechanical Engineers (ASME), 2026)Abstract. A helmet will not fit the same way on different individuals with different head sizes and shapes. However, the degree to which subject-specific fit differences may affect the risk of injury remains understudied. ... -
Age-Related Increases in Graft Tendon Size and Stiffness During Skeletal Growth Enhance Anterior Cruciate Ligament Graft Function and Joint Stability in an Early Adolescent Porcine Model
(The American Society of Mechanical Engineers (ASME), 2026)Abstract. Anterior cruciate ligament (ACL) reconstruction in pediatric patients has a higher graft failure rate compared to adults. Restoring joint stability and reducing graft failure is essential. However, how graft ... -
Subject-Specific Modeling of the Proximal Femur During Falls: Dual Importance of Impact Dynamics and Bone Morphology
(The American Society of Mechanical Engineers (ASME), 2026)Abstract. Clinical risk factors for hip fracture can influence both fall-induced loading and underlying femur morphology/strength; however, these effects are generally studied in isolation. We evaluated the potential effects ... -
Enlarged Internal Carotid Artery Bifurcation Angles May Magnify Hemodynamic Stresses to Facilitate Aneurysm Formation at the Bifurcation
(The American Society of Mechanical Engineers (ASME), 2026)Abstract. This study was to investigate the effect of enlarged internal carotid artery (ICA) bifurcation angles on hemodynamic stresses and direct flow impingement center (DFIC) in facilitating aneurysm formation at the ... -
Biomechanical Variation of the Vessel Wall Along the Length of the Healthy Aorta—Linking Geometric, Flow-, and Pressure-Mediated Adaptations
(The American Society of Mechanical Engineers (ASME), 2026)Abstract. The aorta, the largest artery in the body, exhibits anisotropy and heterogeneity along its length. Over the past several decades, researchers have characterized the positional differences in various geometric and ... -
Fluid Flow Analysis of Pulmonary Hypertension in End-Stage Renal Disease: A Novel Alternative Methods-Driven Case Study
(The American Society of Mechanical Engineers (ASME), 2026)Abstract. Pulmonary hypertension (PH) is a serious condition affecting patients with end-stage renal disease (ESRD), yet the hemodynamic mechanisms underlying development remain poorly understood. Novel alternative methods ... -
Heart Scar-In-A-Dish: Tissue Culture Platform to Study Myocardial Injury and Mechanics In Vitro
(The American Society of Mechanical Engineers (ASME), 2026)Abstract. Myocardial Infarction (MI) occurs when blood flow is blocked to a portion of the left ventricle and leads to necrosis and scar formation. Many therapies are under development to improve infarct healing, and ... -
Heterogenous Lung Model for Blunt Impact Loads Using Strain Rate-Dependent Material Properties of Parenchyma and Bronchi
(The American Society of Mechanical Engineers (ASME), 2026)Abstract. This study aids in the development of a heterogeneous lung model for automobile crashes and blunt trauma. Existing finite element models of the lung tissue are modeled as homogeneous and consider only the parenchyma ... -
Strain Field Mapping Indicates Direct Transmission of Supraspinatus Force Through the Rotator Cuff
(The American Society of Mechanical Engineers (ASME), 2026)Abstract. Operative repair of the rotator cuff (RC) of the shoulder can return a patient to normal function but is not without complications. An understanding of the tissue strains in the RC of the shoulder under normal ... -
Bridging the Gap Between Species: Translating a Fracture Callus Mechanical Properties Model From Ovine to Human Use
(The American Society of Mechanical Engineers (ASME), 2026)Abstract. New approach methodologies (NAMs) can reduce reliance on animal testing and enable outcomes assessments in humans that were previously possible only in animal studies. Translating NAMs from animals to clinical ... -
A New Quantitative Index of Trabecular Bone Microstructural Organization and Its Association With Tissue Failure in Human Vertebrae
(The American Society of Mechanical Engineers (ASME), 2026)Abstract. Trabecular bone is a lightweight porous tissue with critical load-bearing function that is optimized through load-driven structural remodeling. One critical feature of trabecular bone microstructure at the level ... -
Characterization of the Lumbar Spine Dynamic Compression-Flexion Response Until Injury
(The American Society of Mechanical Engineers (ASME), 2026)Abstract. The lumbar spine flexion moment-angle response with superimposed compression serves as the blueprint for spinal behavior and stiffness in the sagittal plane but has rarely been considered at large loads and ... -
Dystrophin Loss in Engineered Heart Tissues Recapitulates Clinically Relevant Aspects of Dystrophic Cardiomyopathy
(The American Society of Mechanical Engineers (ASME), 2026)Abstract. Heart failure is the leading cause of death in patients with Duchenne muscular dystrophy (DMD), but the mechanisms underlying the associated dilated cardiomyopathy (DCM) are not fully understood. To address this ... -
Directed Cell Self-Assembly to Form Tendon and Muscle Models for Studying Early Stages of Musculoskeletal Tissue Formation
(The American Society of Mechanical Engineers (ASME), 2026)Abstract. Nonanimal models (NAMs) provide an important platform for studying musculoskeletal tissue formation under controlled conditions while reducing reliance on vertebrate animal models. In this study, we advanced a ... -
Mechanical Modeling of Cardiac Fibrosis With Explicit Spatial Representation of Cellular Structure and Collagen Alignment
(The American Society of Mechanical Engineers (ASME), 2026)Abstract. Cardiac fibrosis is a pathological condition involving remodeling that impairs cardiac function. Common forms include replacement fibrosis, where damaged myocytes are substituted by collagenous tissue, and ... -
A Probabilistic Method to Model Progressive Metatarsal Displacement and Stiffness During Fatigue Testing
(The American Society of Mechanical Engineers (ASME), 2026)Abstract. To better understand the mechanisms of bone stress injuries (BSI) in metatarsals, we developed an algorithm that adapts finite element (FE) models of metatarsals to simulate fatigue displacements through progressive ...