Journal of Biomechanical Engineering: Recent submissions
Now showing items 341-360 of 5302
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Diffusivity of Human Cartilage Endplates in Healthy and Degenerated Intervertebral Disks
(The American Society of Mechanical Engineers (ASME), 3/28/2023 )The cartilage endplates (CEPs) on the superior and inferior surfaces of the intervertebral disk (IVD), are the primary nutrient transport pathways between the disk and the vertebral body. Passive diffusion is responsible ... -
Bayesian Calibration of Computational Knee Models to Estimate Subject-Specific Ligament Properties, Tibiofemoral Kinematics, and Anterior Cruciate Ligament Force With Uncertainty Quantification
(The American Society of Mechanical Engineers (ASME), 3/28/2023 )High-grade knee laxity is associated with early anterior cruciate ligament (ACL) graft failure, poor function, and compromised clinical outcome. Yet, the specific ligaments and ligament properties driving knee laxity remain ... -
Applications of Finite Element Modeling in Biomechanical Analysis of Foot Arch Deformation: A Scoping Review
(The American Society of Mechanical Engineers (ASME), 5/4/2023 1)Excessive foot arch deformation is associated with plantar tissue overload and ligamentous injury pathologies. Finite element (FE) analysis, as an effective tool for modeling and simulation, has been utilized clinically ... -
Layer-Specific Tensile Strength of the Human Aorta: Segmental Variations
(The American Society of Mechanical Engineers (ASME), 2/6/2023 1)Knowledge of the failure properties of the aorta is essential to understand the mechanisms of dissection and rupture. Limited information is, however, available in humans or experimental animals about the layer-specific ... -
Rate- and Region-Dependent Mechanical Properties of Göttingen Minipig Brain Tissue in Simple Shear and Unconfined Compression
(The American Society of Mechanical Engineers (ASME), 2/6/2023 1)Traumatic brain injury (TBI), particularly from explosive blasts, is a major cause of casualties in modern military conflicts. Computational models are an important tool in understanding the underlying biomechanics of TBI ... -
Lower Extremity Response to Blast Loading: A Computational Study
(The American Society of Mechanical Engineers (ASME), 2/6/2023 1)This study has investigated the response of the Total Human Model for Safety (THUMS) lower extremity finite element model under blast loading. Response of the model was estimated in simulated underbody blast (UBB) loading ... -
Stretch-Induced Uncrimping of Equatorial Sclera Collagen Bundles
(The American Society of Mechanical Engineers (ASME), 12/21/2022)Stretch-induced collagen uncrimping underlies the nonlinear mechanical behavior of the sclera according to what is often called the process of recruitment. We recently reported experimental measurements of sclera collagen ... -
Spatial and Temporal Mapping of Articular Cartilage Poro-Viscoelastic Material Properties Using Indentation
(The American Society of Mechanical Engineers (ASME), 12/9/2022 )Biphasic poro-viscoelastic constitutive material model (BPVE) captures both the fluid flow dependent and independent behavior of cartilage under stress relaxation type indentation. A finite element model based on BPVE ... -
Role of Kidney Stones in Renal Pelvis Flow
(The American Society of Mechanical Engineers (ASME), 2/1/2023 1)Ureteroscopy is a commonly performed medical procedure to treat stones in the kidney and ureter using a ureteroscope. Throughout the procedure, saline is irrigated through the scope to aid visibility and wash-out debris ... -
Biot Theory-Based Finite Element Modeling of Continuous Ultrasound Propagation Through Microscale Articular Cartilage
(The American Society of Mechanical Engineers (ASME), 12/9/2022 )Low-intensity ultrasound has shown promise in promoting the healing and regeneration of articular cartilage degraded by osteoarthritis. In this study, a two-dimensional finite element method (FEM) model was developed for ... -
Experimental Investigation of Dental Composites Degradation After Early Water Exposure
(The American Society of Mechanical Engineers (ASME), 12/9/2022 )While dental composite long-term aging has already been studied in the past, no data exist about the early aging while it might be detrimental regarding the composites' longevity. This study aims to better understand the ... -
Comparison of a Scaled Cadaver-Based Musculoskeletal Model With a Clinical Upper Extremity Model
(The American Society of Mechanical Engineers (ASME), 12/9/2022 )Reliably and accurately estimating joint/segmental kinematics from optical motion capture data has remained challenging. Studies objectively characterizing human movement patterns have typically involved inverse kinematics ... -
Anatomical Characteristics Contributing to Patellar Dislocations Following MPFL Reconstruction: A Dynamic Simulation Study
(The American Society of Mechanical Engineers (ASME), 12/5/2022 )Pathologic anatomy is a primary factor contributing to redislocation of the patella following reconstruction of the medial patellofemoral ligament (MPFL). A pivot landing was simulated following MPFL reconstruction, with ... -
Impact of Blood Rheology on Transition to Turbulence and Wall Vibration Downstream of a Stenosis
(The American Society of Mechanical Engineers (ASME), 12/5/2022 )Previous experimental flow studies have demonstrated a delay (∼20%) in transition to turbulence for whole blood compared to a Newtonian analog fluid in both a straight pipe and eccentric stenosis model with ridged walls. ... -
Anisotropic Mechanical Response of Bovine Pericardium Membrane Through Bulge Test and In-Situ Confocal-Laser Scanning
(The American Society of Mechanical Engineers (ASME), 1/11/2023 )In this work, we present a new experimental setup for the assessment of the anisotropic properties of Bovine Pericardium (BP) membranes. The chemically fixed BP samples have been subjected to a bulge test with in situ ... -
A Computational Study of Dynamic Obstruction in Type B Aortic Dissection
(The American Society of Mechanical Engineers (ASME), 12/21/2022)A serious complication in aortic dissection is dynamic obstruction of the true lumen (TL). Dynamic obstruction results in malperfusion, a blockage of blood flow to a vital organ. Clinical data reveal that increases in ... -
The Accelerated Transcatheter Heart Valve Testing Environment: Loading, Motion, and Fluid Dynamics
(The American Society of Mechanical Engineers (ASME), 12/9/2022 )Transcatheter aortic valve replacements (TAVRs) are an increasingly common treatment for aortic valve disease due to their minimally invasive delivery. As TAVR designs require thinner leaflets to facilitate catheter-based ... -
Dynamic Deformation Calculation of Articular Cartilage and Cells Using Resonance-Driven Laser Scanning Microscopy
(The American Society of Mechanical Engineers (ASME), 10/6/2022 )The deformation of articular cartilage and its cells at the micro-scale during dynamic activities such as gait has high mechanoregulatory importance. Measuring the cellular geometries during such dynamics has been limited ... -
Optimizing the Porohyperelastic Response of a Layered Compliance Matched Vascular Graft to Promote Luminal Self-Cleaning
(The American Society of Mechanical Engineers (ASME), 10/6/2022 )Thrombosis and intimal hyperplasia have remained the major failure mechanisms of small-diameter vascular grafts used in bypass procedures. While most efforts to reduce thrombogenicity have used a biochemical surface ... -
Subcutaneous Drug Delivery: A Review of the State-of-the-Art Modeling and Experimental Techniques
(The American Society of Mechanical Engineers (ASME), 10/11/2022)Delivery of drug formulations through the subcutaneous route is a widely used modality for the treatment of several diseases, such as diabetes and auto-immune conditions. Subcutaneous injections are typically used to inject ...