Journal of Biomechanical Engineering: Recent submissions
Now showing items 241-260 of 5302
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Using a Mock Circulatory Loop as a Regulatory Science Tool to Simulate Different Heart Failure Conditions
(The American Society of Mechanical Engineers (ASME), 2023)Mechanical circulatory support (MCS) device therapy is one of the primary treatment options for end-stage heart failure (HF), whereby a mechanical pump is integrated with the failing heart to maintain adequate tissue ... -
A Numerical Study of Crack Penetration and Deflection at the Interface Between Peritubular and Intertubular Dentin
(The American Society of Mechanical Engineers (ASME), 2024)Dentin is a biological composite exhibiting multilevel hierarchical structure, which confers excellent damage tolerance to this tissue. Despite the progress in characterization of fracture behavior of dentin, the contribution ... -
Computational Study on the Effects of Valve Orientation on the Hemodynamics and Leaflet Dynamics of Bioprosthetic Pulmonary Valves
(The American Society of Mechanical Engineers (ASME), 2024)Pulmonary valves do not display a fibrous annulus as do other valves in the heart; thus, pulmonary valves can be implanted at multiple orientations and locations within the right ventricular outflow tract (RVOT). This gives ... -
How Static and Cyclic Loading Affect the Mechanical Properties of the Porcine Annulus Fibrosus
(The American Society of Mechanical Engineers (ASME), 2024)This study sought to evaluate the effects of prolonged cyclic loading on the tissue-level mechanical properties of the spinal annulus fibrosus. Functional spinal units (FSUs) were obtained from porcine cervical spines at ... -
Detecting Toe-Off and Initial Contact in Real-Time With Self-Adapting Thresholds
(The American Society of Mechanical Engineers (ASME), 2024)This research introduces an adaptive control algorithm designed to determine gait phase in real-time using an inertial measurement unit (IMU) affixed to the shank. Focusing on detecting specific gait events, primarily ... -
Three-Dimensional-Digital Image Correlation Methodology for Kinematic Measurements of Non-Penetrating Blunt Impacts
(The American Society of Mechanical Engineers (ASME), 2024)Blunt force trauma remains a serious threat to many populations and is commonly seen in motor vehicle crashes, sports, and military environments. Effective design of helmets and protective armor should consider biomechanical ... -
Enzymatic Digestion of the Intervertebral Disc Alters Intradiscal Injection and Leakage Mechanics
(The American Society of Mechanical Engineers (ASME), 2024)Intradiscal injection is required to deliver therapeutic agents to the intervertebral disc (IVD) nucleus pulposus (NP). However, injectate leakage following needle retraction may result in decreased treatment efficacy and ... -
Experimental Analysis of Robotic Cortical Bone Specimen Drilling Performance: Effect of Cryogen
(The American Society of Mechanical Engineers (ASME), 2024)In orthopedic surgery, precise bone screw insertion is crucial for stabilizing fractures, necessitating a preliminary cortical bone drilling procedure. However, this process can induce temperatures exceeding 70 °C due to ... -
A Mathematical Model for Postimplant Collagen Remodeling in an Autologous Engineered Pulmonary Arterial Conduit
(The American Society of Mechanical Engineers (ASME), 2024)This study was undertaken to develop a mathematical model of the long-term in vivo remodeling processes in postimplanted pulmonary artery (PA) conduits. Experimental results from two extant ovine in vivo studies, wherein ... -
Residual Strain and Joint Pressurization Maintain Collagen Tension for On-Joint Lumbar Facet Capsular Ligaments
(The American Society of Mechanical Engineers (ASME), 2024)Modeling the lumbar facet capsular ligament's (FCL) mechanical behavior under various physiological motions has often been a challenge due to limited knowledge about the on-joint in situ ligament state arising from attachment ... -
Analysis of Variation in Sagittal Curvature of the Femoral Condyles
(The American Society of Mechanical Engineers (ASME), 2024)In designing femoral components, which restore native (i.e., healthy) knee kinematics, the flexion–extension (F-E) axis of the tibiofemoral joint should match that of the native knee. Because the F–E axis is governed by ... -
Optimal Implant Positioning Following Total Knee Arthroplasty Using Predictive Dynamic Simulation
(The American Society of Mechanical Engineers (ASME), 2024)In this paper, a novel method is proposed for the determination of the optimal subject-specific placement of knee implants based on predictive dynamic simulations of human movement following total knee arthroplasty (TKA). ... -
Effects of Time-Dependent Adenosine Triphosphate Consumption Caused by Neuron Firing on Adenosine Triphosphate Concentrations in Synaptic Boutons Containing and Lacking a Stationary Mitochondrion
(The American Society of Mechanical Engineers (ASME), 2024)The precise mechanism behind the supply of adenosine triphosphate (ATP) to approximately half of the presynaptic release sites in axons that lack a stationary mitochondrion is not fully understood. This paper presents a ... -
Effects of Fetal Position on the Loading of the Fetal Brain During the Onset of the Second Stage of Labor
(The American Society of Mechanical Engineers (ASME), 2024)During vaginal delivery, the delivery requires the fetal head to mold to accommodate the geometric constraints of the birth canal. Excessive molding can produce brain injuries and long-term sequelae. Understanding the ... -
Critical Examination of Methods to Determine Tibiofemoral Kinematics and Tibial Contact Kinematics Based on Analysis of Fluoroscopic Images
(The American Society of Mechanical Engineers (ASME), 2024)Goals of knee replacement surgery are to restore function and maximize implant longevity. To determine how well these goals are satisfied, tibial femoral kinematics and tibial contact kinematics are of interest. Tibiofemoral ... -
Comparison of the Kinematics and Laxity of Total Knee Arthroplasty Bearing Designs Stabilized With Specimen-Specific Virtual Ligaments on a Joint Motion Simulator
(The American Society of Mechanical Engineers (ASME), 2024)A variety of total knee arthroplasty (TKA) designs offer increased congruency bearing options, primarily to compensate for a loss of posterior cruciate ligament (PCL) function. However, their efficacy in providing sufficient ... -
Predicting Knee Joint Contact Forces During Normal Walking Using Kinematic Inputs With a Long-Short Term Neural Network
(The American Society of Mechanical Engineers (ASME), 2024)Knee joint contact forces are commonly estimated via surrogate measures (i.e., external knee adduction moments or musculoskeletal modeling). Despite its capabilities, modeling is not optimal for clinicians or persons with ... -
Sensitivity of Phonation Onset Pressure to Vocal Fold Stiffness Distribution
(The American Society of Mechanical Engineers (ASME), 2024)Phonation onset is characterized by the unstable growth of vocal fold (VF) vibrations that ultimately results in self-sustained oscillation and the production of modal voice. Motivated by histological studies, much research ... -
Computational Pulsatile Flow and Efficiency Analysis of Biocompatible Microfluidic Artificial Lungs for Different Fiber Configurations
(The American Society of Mechanical Engineers (ASME), 2024)Average-sized microfluidic artificial lungs consisting of rows and columns of fiber bundles with different column to row aspect ratios (AR) are numerically analyzed for flow characteristics, maximum gas transfer performance, ... -
Equilibrium Mechanical Properties of the Nonhuman Primate Cervix
(The American Society of Mechanical Engineers (ASME), 2024)Cervical remodeling is critical for a healthy pregnancy. Premature tissue changes can lead to preterm birth (PTB), and the absence of remodeling can lead to post-term birth, causing significant morbidity. Comprehensive ...