Abstract: New approach methodologies, nonanimal methods, and novel alternative methods are all used to define the acronym for NAMs. While there may not be consensus on the words that made the acronym, there is certainly consensus ...

Abstract: Platelet contractile forces play a major role in clot retraction and help to hold hemostatic clots against the vessel wall. Platelet forces are produced by its cytoskeleton, which is composed of actin and nonmuscle myosin ...

Abstract: The interplay between the mechanical properties of cells and the forces that they produce internally or that are externally applied to them play an important role in maintaining the normal function of cells. These forces ...

Abstract: Abstract. Heart failure is the leading cause of death in patients with Duchenne muscular dystrophy (DMD), but the mechanisms underlying the associated dilated cardiomyopathy (DCM) are not fully understood. To address this ...

Abstract: Human stem cellderived cardiomyocytes hold promise for heart repair, disease modeling, drug screening, and for studies of developmental biology. All of these applications can be improved by assessing the contractility of ...