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Dystrophin Loss in Engineered Heart Tissues Recapitulates Clinically Relevant Aspects of Dystrophic Cardiomyopathy
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Abstract. Heart failure is the leading cause of death in patients with Duchenne muscular dystrophy (DMD), but the mechanisms underlying the associated dilated cardiomyopathy (DCM) are not fully understood. To address this ...
A Novel Small-Specimen Planar Biaxial Testing System With Full In-Plane Deformation Control
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Simulations of soft tissues require accurate and robust constitutive models, whose form is derived from carefully designed experimental studies. For such investigations of membranes or thin specimens, planar biaxial systems ...
Long-Term Effects of Reproduction and Lactation on the Rat Supraspinatus Tendon and Proximal Humerus
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: During pregnancy and breastfeeding, women undergo hormonal fluctuations required for fetal development, parturition, and infant growth. These changes have secondary consequences on the maternal musculoskeletal system, ...
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