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Controlled Stiffness of Direct-Write, Near-Field Electrospun Gelatin Fibers Generates Differences in Tenocyte Morphology and Gene Expression
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Tendinopathy is a leading cause of mobility issues. Currently, the cell–matrix interactions involved in the development of tendinopathy are not fully understood. In vitro tendon models provide a unique tool for addressing ...
Age-Related Increases in Graft Tendon Size and Stiffness During Skeletal Growth Enhance Anterior Cruciate Ligament Graft Function and Joint Stability in an Early Adolescent Porcine Model
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Abstract. Anterior cruciate ligament (ACL) reconstruction in pediatric patients has a higher graft failure rate compared to adults. Restoring joint stability and reducing graft failure is essential. However, how graft ...
Neo-Natal Castration Leads to Subtle Differences in Porcine Anterior Cruciate Ligament Morphology and Function in Adolescence
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Female adolescent athletes are at a higher risk of tearing their anterior cruciate ligament (ACL) than male counterparts. While most work related to hormones has focused on the effects of estrogen to understand the increased ...
An Exploratory Assessment of Associations Between Serum Estrogen to Progesterone Ratio and Anterior Cruciate Ligament Size, Biomechanics, and T2* Relaxation Time in the Porcine Model
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Abstract. Adolescent females are at a higher risk of anterior cruciate ligament (ACL) injury than males. While prior studies have associated injury timing and menstrual cycle phase, these data are limited by indirect cycle ...
A Systems Approach to Biomechanics, Mechanobiology, and Biotransport
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The human body represents a collection of interacting systems that range in scale from nanometers to meters. Investigations from a systems perspective focus on how the parts work together to enact changes across spatial ...
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