Abstract: This paper presents a multiscale dynamic model for the simulation and analysis of flexibility in myosin V. A 3D finite segment model, a multirigid body model connected with torsional springs, is developed to mechanically ...

Abstract: This work investigates the modification of the Nóse–Hoover thermostat, a well-known tool for controlling system temperature in nanoscale dynamical simulations. Nóse–Hoover response is characterized by a mean temperature ...

Abstract: Molecular dynamics simulations require significant computational resources to generate modest time evolutions. Large active forces lead to large accelerations, requiring subfemtosecond integration time steps to capture the ...

Abstract: Microscale dynamic simulations can require significant computational resources to generate desired time evolutions. Microscale phenomena are often driven by even smaller scale dynamics, requiring multiscale system definitions ...

Abstract: Microscale dynamic simulations can require significant computational resources to generate desired time evolutions. Microscale phenomena are often driven by even smaller scale dynamics, requiring multiscale system definitions ...

Abstract: Biomolecular simulations are computationally expensive. Simulating time histories larger than seconds remain elusive even with the help of supercomputers. Biological phenomena are multiscale in nature. The dynamics range ...

Abstract: This paper presents a high-speed approach to simulating the long-term mechanobiological development of stem cells during the adipogenesis process. A novel three-dimensional model of human bone marrow-derived mesenchymal ...

Abstract: This paper presents a high-speed approach to simulating the long-term mechanobiological development of stem cells during the adipogenesis process. A novel three-dimensional model of human bone marrow-derived mesenchymal ...