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RISEffect of Moderate Stenosis on the Upstream and Downstream Flow Patterns in the Internal Carotid Artery—An in vitro Investigation
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Abstract. Narrowing of the internal carotid artery (ICA), known as stenosis, can significantly alter normal blood flow and increase the likelihood of cerebrovascular complications such as ischemic stroke. This study presents ...
Numerical Study of Transport of Anticancer Drugs in Heterogeneous Vasculature of Human Brain Tumors Using Dynamic Contrast Enhanced-Magnetic Resonance Imaging
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Systemic administration of drugs in tumors is a challenging task due to unorganized microvasculature and nonuniform extravasation. There is an imperative need to understand the transport behavior of drugs when administered ...
Effect of Tumor Volume on Drug Delivery in Heterogeneous Vasculature of Human Brain Tumors
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Drug distribution in tumors is strongly dependent on tumor biological properties such as tumor volume, vasculature, and porosity. An understanding of the drug distribution pattern in tumors can help in enhancing the ...