http://yetl.yabesh.ir/yetl1/handle/yetl/19058 2026-04-14T00:13:50Z http://yetl.yabesh.ir/yetl1/handle/yetl/159266 Creation of Highly Defined Mesenchymal Stem Cell Patterns in Three Dimensions by Laser Assisted Bioprinting Pagأ¨s, Emeline; Rأ©my, Murielle; Kأ©riquel, Virginie; Correa, Manuela Medina; Guillotin, Bertrand; Guillemot, Fabien Bioprinting is a technology that allows making complex tissues from the bottomup. The need to control accurately both the resolution of the printed droplet and the precision of its positioning was reported. Using a bioink with 1 أ— 108 cells/mL, we present evidence that the laserassisted bioprinter (LAB) can deposit droplets of functional mesenchymal stem cells with a resolution of 138 آ±â€‰28 خ¼m and a precision of 16 آ±â€‰13 خ¼m. We demonstrate that this high printing definition is maintained in three dimensions. 2015-01-01T00:00:00Z http://yetl.yabesh.ir/yetl1/handle/yetl/159268 Three Dimensional Printing Based Hybrid Manufacturing of Microfluidic Devices Alapan, Yunus; Hasan, Muhammad Noman; Shen, Richang; Gurkan, Umut A. Microfluidic platforms offer revolutionary and practical solutions to challenging problems in biology and medicine. Even though traditional micro/nanofabrication technologies expedited the emergence of the microfluidics field, recent advances in advanced additive manufacturing hold significant potential for singlestep, standalone microfluidic device fabrication. One such technology, which holds a significant promise for next generation microsystem fabrication is threedimensional (3D) printing. Presently, building 3D printed standalone microfluidic devices with fully embedded microchannels for applications in biology and medicine has the following challenges: (i) limitations in achievable design complexity, (ii) need for a wider variety of transparent materials, (iii) limited zresolution, (iv) absence of extremely smooth surface finish, and (v) limitations in precision fabrication of hollow and void sections with extremely high surface area to volume ratio. We developed a new way to fabricate standalone microfluidic devices with integrated manifolds and embedded microchannels by utilizing a 3D printing and laser micromachined lamination based hybrid manufacturing approach. In this new fabrication method, we exploit the minimized fabrication steps enabled by 3D printing, and reduced assembly complexities facilitated by laser micromachined lamination method. The new hybrid fabrication method enables key features for advanced microfluidic system architecture: (i) increased design complexity in 3D, (ii) improved control over microflow behavior in all three directions and in multiple layers, (iii) transverse multilayer flow and precisely integrated flow distribution, and (iv) enhanced transparency for high resolution imaging and analysis. Hybrid manufacturing approaches hold great potential in advancing microfluidic device fabrication in terms of standardization, fast production, and userindependent manufacturing. 2015-01-01T00:00:00Z http://yetl.yabesh.ir/yetl1/handle/yetl/159270 Discussion: “A Review and Parametric Investigation Into Nanofluid Viscosity Modelsâ€‌ (Nwosu, P. N., Meyer, J., and Sharifpur, M., 2014, ASME J. Nanotechnol. Eng. Med., 5(3), p. 031008) Awad, M. M. Nwosu et al. [1] mentioned the empirical model of Maأ¯ga et al. [2] for ethylene glycol (EG)–خ³Al2O3 nanofluid. It should be noted that Nwosu et al. [1] did not mention the empirical model of Maأ¯ga et al. [2] for water–خ³Al2O3 nanofluid. This empirical model for water–خ³Al2O3 nanofluid wasDisplay Formula(1)خ·=خ·nfخ·bf=1+7.3د•+123د•2Nwosu et al. [1] mentioned the empirical models of Nguyen et al. [3] for Al2O3/H2O nanofluid with various particles sizes of 47 and 36 nm, respectively. It should be noted that Nwosu et al. [1] did not mention the empirical model of Nguyen et al. [3] for CuO/H2O nanofluid with 29 nm particle size. This empirical model for CuO/H2O nanofluid wasDisplay Formula(2)خ·=خ·nfخ·bf=1.475−0.319د•+0.051د•2+0.009د•3Also, it should be noted that the correct form of Eq. (21) in the paper of Nwosu et al. [1] based on the study of Nguyen et al. [3] isDisplay Formula(3)خ·=خ·nfخ·bf=1.1250−0.0007TThat is, the second term on the righthand side is −0.0007T and not −0.007T. 2015-01-01T00:00:00Z http://yetl.yabesh.ir/yetl1/handle/yetl/159269 Scaffold Based or Scaffold Free Bioprinting: Competing or Complementing Approaches? Ozbolat, Ibrahim T. Bioprinting is an emerging technology to fabricate artificial tissues and organs through additive manufacturing of living cells in a tissuesspecific pattern by stacking them layer by layer. Two major approaches have been proposed in the literature: bioprinting cells in a scaffold matrix to support cell proliferation and growth, and bioprinting cells without using a scaffold structure. Despite great progress, particularly in scaffoldbased approaches along with recent significant attempts, printing largescale tissues and organs is still elusive. This paper demonstrates recent significant attempts in scaffoldbased and scaffoldfree tissue printing approaches, discusses the advantages and limitations of both approaches, and presents a conceptual framework for bioprinting of scaleup tissue by complementing the benefits of these approaches. 2015-01-01T00:00:00Z